abstract：:Hair's importance in human communication means that abnormalities like excess hair in hirsutism or hair loss in alopecia cause psychological distress. Androgens are the main regulator of human hair follicles, changing small vellus follicles producing tiny, virtually invisible hairs into larger intermediate and termina...

journal_title：Dermatologic therapy

authors： Randall VA

更新日期：2008-09-01 00:00:00

abstract：:The major therapeutic approaches (5-fluorouracil, imiquimod, vermilionectomy, and CO(2) Laser ablation) for actinic cheilitis are aimed at avoiding and preventing a malignant transformation into invasive squamous cell carcinoma via destruction/removal of the damaged epithelium. Recently, photodynamic therapy (PDT) has...

journal_title：Dermatologic therapy

authors： Rossi R,Assad GB,Buggiani G,Lotti T

更新日期：2008-09-01 00:00:00

abstract：:Chronic venous leg ulcers (CVLU) are chronic wounds, associated with long-standing venous hypertension, which have a poor prognosis for healing. In the process of wound healing the first step is represented by platelet aggregation and subsequent release of growth factors and other mediators, which play a key role in t...

journal_title：Dermatologic therapy

authors： Ficarelli E,Bernuzzi G,Tognetti E,Bussolati O,Zucchi A,Adorni D,De Panfilis G

更新日期：2008-07-01 00:00:00

abstract：:This article presents a short summary of our current knowledge of cicatricial alopecia disease pathogenesis and the hypothetical disease mechanisms that may be involved in scarring alopecia development. Several forms of scarring alopecia likely involve targeted cytotoxic action against hair follicle cells mediated by ...

journal_title：Dermatologic therapy

authors： McElwee KJ

更新日期：2008-07-01 00:00:00

abstract：:Genital ulcer disease (GUD) constitutes a major public health problem. Most of them are the result of sexually transmitted diseases. Genital herpes, syphilis, lymphogranuloma venereum, granuloma venereum, or chancroid are the commonly encountered GUD. The treatment modalities for these disorders have changed with adve...

journal_title：Dermatologic therapy

authors： Kaliaperumal K

更新日期：2008-05-01 00:00:00

abstract：:Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...

journal_title：Dermatologic therapy

authors： Accordino RE,Engler D,Ginsburg IH,Koo J

更新日期：2008-01-01 00:00:00

abstract：:Male cosmetic patients represent a growing population of individuals who can substantially benefit from well-chosen esthetic interventions. Understanding some of the unique aspects of the male psyche can result in more effective recruitment of male cosmetic patients and aid the clinician in helping these patients to c...

journal_title：Dermatologic therapy

authors： Fried RG

更新日期：2007-11-01 00:00:00

abstract：:Growth factors play an important role in reversing the effects of skin aging mediated by chronological and environmental factors. Excessive oxidation of intra- and extracellular components result in breakdown of collagen and elastin network in the dermis and produce the effect of facial aging. Topical application of h...

journal_title：Dermatologic therapy

authors： Mehta RC,Fitzpatrick RE

更新日期：2007-09-01 00:00:00

abstract：:Tumor necrosis-alpha (TNF-alpha) has been implicated in many forms of inflammation and is an end-stage product of the inflammatory cytokine cascade. It is an inducer of inflammation and is involved in many cutaneous and systemic inflammatory diseases. The development of agents that block the effects of TNF-alpha has a...

journal_title：Dermatologic therapy

authors： Jackson JM

更新日期：2007-07-01 00:00:00

abstract：:Smooth, lustrous nails are a sign of health and beauty in our society and fuel the US$6-billion nail salon industry in the United States. Although many women can use nail cosmetics without adverse consequences, when problems occur it is important to recognize the causes and treat the problem condition. The cornerstone...

journal_title：Dermatologic therapy

authors： Chang RM,Hare AQ,Rich P

更新日期：2007-01-01 00:00:00

abstract：:Clinical research plays a very important role in the development of drugs and devices, including those for wound healing. The process of initiating a clinical trial can be rather daunting, particularly with the ever-increasing regulatory hurdles. Many clinicians are generally either not trained or have limited knowled...

journal_title：Dermatologic therapy

authors： Carson PA

更新日期：2006-11-01 00:00:00

abstract：:Both in the topical and systemic treatment of psoriasis, retinoids are mainstays. In this chapter the history and modes of actions of retinoids are presented. Tazarotene and acitretin are the only retinoids that are available in both topical and systemic formulations. A more extensive description of their pharmacology...

journal_title：Dermatologic therapy

authors： van de Kerkhof PC

更新日期：2006-09-01 00:00:00

abstract：:The isotretinoin registry has arrived. It has a lofty goal of preventing all isotretinoin pregnancies. How we got to this point and what the registry means to prescribers and patients have many dermatologists confused and concerned. Will it be burdensome, will it preclude the use in most offices of this most important...

journal_title：Dermatologic therapy

authors： Baldwin HE

更新日期：2006-07-01 00:00:00

abstract：:Atopic dermatitis is an extremely common childhood skin disease that can have far-reaching impact on patients and families. Pediatric patients, particularly infants, pose special concerns for parents and providers, and equal emphasis must be placed on both nonpharmacologic and prescription interventions. Concerns for ...

journal_title：Dermatologic therapy

authors： Sidbury R,Poorsattar S

更新日期：2006-03-01 00:00:00

abstract：:The care of patients who have cutaneous melanoma (CM) has undergone a dramatic change during the past five decades. In an increasing majority of cases, CM is being discovered in a premetastatic phase of tumor progression. Most patients are being treated in the ambulatory setting with a minimum of inconvenience and eco...

journal_title：Dermatologic therapy

authors： Rhodes AR

更新日期：2006-01-01 00:00:00

abstract：:The specific pathway of "pure," histaminergic itch is traced from the mechano-insensitive nerve fibers in the skin to their central cortical projections. Neuropathic itch created at different levels of this anatomical pathway is reviewed. In this review the present author discusses damage to pruritoceptors in the skin...

journal_title：Dermatologic therapy

authors： Wallengren J

更新日期：2005-07-01 00:00:00

abstract：:Itch is an extremely frequent and enervating symptom of many diseases. Current anti-itch therapy, which is based almost exclusively on an "immunocentric" viewpoint, is often unsatisfactory. Recent studies show that this symptom is in fact the result of a complex interplay among skin, nervous system, endocrine system, ...

journal_title：Dermatologic therapy

authors： Guarneri C,Terranova M,Terranova G,Guarneri F

更新日期：2005-07-01 00:00:00

abstract：:There are many developmental abnormalities that may appear in the neonate and in infants when critical steps in embryogenesis fail. These steps are often not fatal but can lead to significant morbidity for those patients affected. A logical approach is needed in addressing both the diagnostic and therapeutic issues th...

journal_title：Dermatologic therapy

authors： Farvolden D,Sweeney SM,Wiss K

更新日期：2005-03-01 00:00:00

abstract：:Solid organ transplant recipients are at a significantly increased risk of developing skin cancer. Both systemic and topical retinoids are useful for chemosuppression of skin cancer in this patient population. These drugs can reduce both the present extent and the future development of premalignant and malignant skin ...

journal_title：Dermatologic therapy

authors： Neuhaus IM,Tope WD

更新日期：2005-01-01 00:00:00

abstract：:Protozoan infections can have a variety of different cutaneous manifestations in addition to systemic signs and symptoms of disease. Recognition and diagnosis can be difficult, as additional laboratory tests, in addition to biopsies, may be required. Treatment options for different protozoa vary and resolution of dise...

journal_title：Dermatologic therapy

authors： Sra KK,Sracic J,Tyring SK

更新日期：2004-01-01 00:00:00

abstract：:Although there is still some controversy about the existence of psoriatic arthritis as a specific form of inflammatory arthritis associated with psoriasis, epidemiological, and clinical studies support the unique features of psoriatic arthritis. Because of lack of diagnostic or classification criteria, the disease has...

journal_title：Dermatologic therapy

authors： Gladman DD

更新日期：2004-01-01 00:00:00

abstract：:Desquamative inflammatory vaginitis (DIV) is not a diagnosis in itself, and may be the presentation of a range of blistering disorders including pemphigus vulgaris, lichen planus and mucous membrane pemphigoid. The existence of an idiopathic subset of DIV remains controversial and is discussed in the present article. ...

journal_title：Dermatologic therapy

authors： Murphy R

更新日期：2004-01-01 00:00:00

abstract：:Hand dermatitis is a common skin condition that often has a chronic and/or relapsing clinical course. Several clinical forms of hand dermatitis have been described, including contact (i.e., allergic and irritant), hyperkeratotic (i.e., psoriasiform or tylotic), frictional, nummular, atopic, pompholyx (i.e., dyshidrosi...

journal_title：Dermatologic therapy

authors： Warshaw EM

更新日期：2004-01-01 00:00:00

abstract：:Cumulative exposure to ultraviolet radiation (UVR) increases the risk of developing skin cancer, particularly squamous cell carcinoma and basal cell carcinoma. Thus, the need for protection from the sun is widely advocated, but consumers generally associate such protection with the occasional extreme exposure and tend...

journal_title：Dermatologic therapy

authors： Nole G,Johnson AW

更新日期：2004-01-01 00:00:00

abstract：:Alternative methods are commonly used in patients with dermatologic diseases, with homeopathy being one of the most common. Homeopathy was developed by Samuel Hahnemann (1755-1843) and is based on the law of similars and the law of infinitesimals. It is a regulatory therapy where high dilutions of particular compounds...

journal_title：Dermatologic therapy

authors： Smolle J

更新日期：2003-01-01 00:00:00

abstract：:Photodermatoses can be classified into five general categories: 1) idiopathic photodermatoses, including polymorphic light eruption (PMLE), actinic prurigo, hyroa vacciniforme, chronic actinic dermatitis, and solar urticaria; 2) photodermatoses which are secondary to exogenous agents, including phototoxic and photoall...

journal_title：Dermatologic therapy

authors： Yashar SS,Lim HW

更新日期：2003-01-01 00:00:00

abstract：:This article refers to papulosquamous diseases that are seen in the elderly. Many of these diseases are complex to diagnose due to the fact that they are difficult to identify, because they may resemble a similar disorder, which can be misleading. The problem that is frequently seen with these diseases is that they ar...

journal_title：Dermatologic therapy

authors： Norman RA,Blanco PM

更新日期：2003-01-01 00:00:00

abstract：:Experience at the University of California, San Francisco (UCSF), in the management of patch-stage mycosis fungoides (MF) with topical, predominantly high-potency, corticosteroids is reviewed. The technique of applications is discussed in detail. Approximately 200 patients have been treated. The results are very favor...

journal_title：Dermatologic therapy

authors： Zackheim HS

更新日期：2003-01-01 00:00:00